If I develop a pharmaceutical agent that interacts with approximately 70% of the receptors in your brain, we can anticipate that it will produce significant effects, both therapeutic and adverse.

PMDD can quietly take control of a woman’s life for part of every month. The emotional changes feel intense, sudden, and hard to explain to others. Many women know something feels wrong, but struggle to name it. Here’s how PMDD affects mood, relationships, and daily life, and why proper understanding matters.